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Scientific Considerations for Communicating Risks Associated with Talc (PSX 2021 On Demand)



Course Description:
Talc is a mineral mined worldwide for use in a wide range of consumer products. Some talc deposits can co-occur naturally with deposits of serpentine or amphibole minerals, raising the issue of whether trace levels of these minerals may contaminate talc-containing products. The presence of serpentine or amphibole minerals can potentially elevate end users' risk of mesothelioma through inhalation exposures. Standardized sensitive analytical methods can be used to screen for serpentine and amphibole minerals. However, product stewards must properly interpret the resulting data to avoid misrepresenting potential exposures, resulting in incorrect or misleading conclusions about mesothelioma risks.

This session will discuss communicating risk to stakeholders and making risk management decisions if serpentine or amphibole materials are detected in products. Specifically, the speaker will cover four scientific considerations related to mesothelioma risks: the epidemiology of mesothelioma among talc-exposed cohorts; the distinction of mesothelioma hazard between and within mineral types and habits; quantitative contextualization of analytical content data with relevant benchmarks; and influence of encapsulation and matrix effects on the release of these minerals. This session will draw upon the most up-to-date scientific information available on talc and asbestos, given the latter's potential association with talc.

Contact Hours:
0.5 Contact Hours

Presentation Date:
09/29/2021

Presenters:
Ryan Lewis PhD, CIH, Exponent, Inc.
Sarah Dahlberg MS, Exponent, Inc.